Zofran is generically known as Ondansetron. It is a medicine that inhibits natural chemicals called serotonin that is responsible for nausea and vomiting. Zofran helps in the prevention of vomiting and nausea which can be from cancer chemotherapy, radiation treatment or surgery.
Zofran as a potent drug works effectively with other drugs for the prevention of nausea and vomiting that are caused by cancer chemotherapy and radiation therapy. Zofran also helps with the treatment and prevention of vomiting and nausea that may be caused by surgery. Zofran is basically seen as a serotonin inhibitor which blocks the chemicals that are responsible for vomiting.
Mode of Indication, Dosage, and Duration of Treatment
You should endeavor to adhere to all instructions given specifically by your doctor. It is advisable to read carefully the prescription label and observe duly the directions therein. Ensure you take Zofran accordingly as prescribed; not more, less or longer than it is required. You can take Zofran with or without a meal. You are advised to take your first dose before the surgery, radiation treatment or cancer chemotherapy. Ensure that Zofran tablet is taken with enough quantity of water (a full glass will do). For Zofran orally disintegrating tablet, you are advised to properly keep it in the provided blister pack if not in use. Before use, unseal the package and unpeel the foil. This should be done with care so that the drug will not be damaged. Ensure that you dry your hands before removing the tablet. Put the tablet in your mouth to be dissolved – do not swallow until it dissolves. For appropriate dose measurement, endeavor to use a dose-measuring device.
The following precautions should be taken before or when using Ondansetron:
- Patients that are hypersensitive to Ondansetron or other related medications such as palonosetron, granisetron or dolasetron should away from the use of Zofran.
- Patients on Apokyn should keep away from the use of Zofran.
- You are advised to bring any of the following medical conditions into your doctor’s awareness:
- The disease of the liver;
- Digestive tract blockage;
- Slow heartbeats;
- Long QT syndrome;
- An electrolyte imbalance;
- Congestive heart failure.
- Pregnant women are advised to seek the advice of their doctors before using Ondansetron.
- Lactating mothers should seek the advice of their doctors before the use of Zofran.
- Children under the age of 4 years old are restricted from the use of Ondansetron.
- Patients with phenylketonuria should notify their doctors before the use of Zofran.
Ensure that you request for medical advice if you begin to experience the symptoms of hypersensitivity to Zofran such as difficulty breathing, rash, fever, hives, chills, and swollen lips, tongue, face or throat. The following are the common side effects of Zofran:
Peradventure you take more than the prescribed doses, quickly see your doctor or call for emergency medical help. The signs of Overdose may involve the following:
- Sudden vision loss;
- Feeling light-headed;
- Severe constipation.
Interaction with other drugs
You should put into cognizance to notify your doctor about the intake of some medications with Zofran. Medications such as antidepressants, antipsychotic medicines, antibiotics, rhythm medicine, and drugs the treatment of HIV/AIDS, malaria or cancer should not be used together with Ondansetron. This may result in serious heart problem. The intake of Zofran medicine with other medications may also lead to serotonin syndrome which may be deadly. Ensure you keep your doctor abreast of any of the following medications:
- Depressive disorder medicine;
- Nausea and vomiting preventive medication;
- Opioid Medication;
- Psychiatric disorder medicine;
Additionally, the following drugs may interact with Ondansetron:
- Prescription and over-the-counter medicines;
- Herbal products.